The Role of Src Kinase in Macrophage-Mediated Inflammatory Responses

Table 5

Naturally occurring compounds inhibiting Src pathway activation in macrophages.

Compound	Action target of Src	Reference
Saurolactam	Inhibition of osteoclast differentiation and stimulation of apoptosis in mature osteoclasts.	[103]
Cytochalasin B	Suppression of actin cytoskeleton rearrangement	[104]
Butyrate	Reduction of lipopolysaccharide-mediated macrophage migration	[105]
RHS-0110; (Kojic acid derivative)	Suppression of LPS-induced NO production and interleukin- (IL-) 6 expression	[106]
Maslinic acid	Suppression of RANKL-induced osteoclastogenesis	[107]
Glabridin	Suppression of RANKL-induced osteoclastogenesis	[108]
Morelloflavone	Inhibition of migration-related kinases, amelioration of atherosclerosis in mice	[109]
Arctigenin	Suppression of (RANKL-) mediated osteoclast differentiation	[110]
Kahweol	Prevention of osteoclastogenesis	[111]