Anti-Inflammatory Properties of Sirtuin 6 in Human Umbilical Vein Endothelial Cells
Figure 9
SIRT6 regulates proinflammatory mediators via NF-B. HUVECs were cotransfected with 1 g negative control construct and NF-B reporter construct, along with 1 g empty or SIRT6 pCMV6 vector for 72 h. (a) IL-6 and (b) , concentration in condition medium. Each bar represents the mean SEM ( experiments). versus cells transfected with NF-B reporter plus empty pCMV6 vector.
