Diverse Roles of Macrophages in Atherosclerosis: From Inflammatory Biology to Biomarker Discovery

<table>Signalling pathways in a macrophage involved in atherosclerosis. Pro- and anti-inflammatory factors act on macrophages, leading to activation of downstream scavenger receptors (SRs)/toll-like receptors (TLRs)-NF-<i>κ</i>B signalling, endoplasmic reticulum (ER) stress and efflux of cholesterol via ABCA and ABCG transporters.</table>

Mediators of Inflammation

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Figure 2

Figure 2: Diverse Roles of Macrophages in Atherosclerosis: From Inflammatory Biology to Biomarker Discovery 