Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst
Figure 2
SOD3 downregulated arthritis in wild-type B10.Q mice. Adenovirally expressed SOD3 reduced arthritis severity in the treated paws (a) in wild-type B10.Q mice (Ade-SOD3 , Ade-lacZ ). When compared to the PBS-treated injection control () group, Ade-SOD3-treated mice had less increase in the arthritis score in the treated paw than the Ade-LacZ-treated control mice (b).