Association between Polymorphisms in Interleukin-17A and -17F Genes and Chronic Periodontal Disease

Table 4

Association between IL-17A G197A and IL-17F C7488T polymorphisms and clinicopathological features of chronic periodontitis.

Genotype	𝑛	PD (mm)	𝑃 value	CAL (mm)	𝑃 value	BOP (%)	𝑃 value
IL-17A G197A
AA/AG	24	4.82*	0.012	6.00*	0.004	33.40	0.31
AA	15	4.58*	0.005	5.77*	0.01	39.45	0.14
AG	9	5.29*	0.007	6.429*	0.004	22.14	1.00
GG	6	3.30		4.70		23.75
IL-17F C7488T
CT/TT	19	4.86	0.11	5.571	0.14	25.89	0.27
TT	6	4.91	0.20	5.63	0.16	25.24	0.25
CT	13	4.67	0.18	6.67	0.59	28.30	0.71
CC	11	5.25		6.25		37.33

PD: probing depth, CAL: clinical attachment loss, and BOP: bleeding on probing.
*Significantly different from GG or CC genotype (𝑃<0.05, Student’s 𝑡-test).