Simulating Sleep Apnea by Exposure to Intermittent Hypoxia Induces Inflammation in the Lung and Liver

Table 1

The effect of intermittent hypoxia on hepatic lipid peroxidation as shown by the TBARS assay and liver antioxidant enzyme activity.

		SIH	IH	𝑃 value
Liver	TBARS(nmol/mg prot)	2.90 ± 0.23	3.76 ± 0.15	0.0389
	SOD(USOD/mg prot)	3.13 ± 0.53	5.86 ± 0.70	0.0118
	CAT(nmol/mg prot)	0.82 ± 0.17	2.33 ± 0.09	0.0015
Lung	TBARS(nmol/mg prot)	4.57 ± 0.10	5.22 ± 0.10	0.0116
	SOD(USOD/mg prot)	7.27 ± 0.99	4.64 ± 0.22	0.0272
	CAT(nmol/mg prot)	2.62 ± 0.18	3.48 ± 0.13	0.0042

Results are reported as mean ± standard error, 𝑛=6 per group. 𝑃 value according to Student’s 𝑡-test.
SIH: sham intermittent hypoxia group; IH: intermittent hypoxia.
SOD: superoxide dismutase; CAT: catalase.