Oleic Acid Induces Lung Injury in Mice through Activation of the ERK Pathway
Figure 3
Intratracheal administration of OA failed to induce inflammation in TLR4 mutant C57B10/ScCr mice. Neutrophil (a) and protein (b) accumulation in BALF 24 h after stimulation of C57B10/ScCr (white bars) or C57B10 (dark bars) with OA and LPS. Control animals received PBS. Results are mean ± SEM from at least 11 animals. The experiment was repeated 3 times with similar results. * compared to control group. ** C57B10/ScCr compared to C57B10 group for LPS.
