Oleic Acid Induces Lung Injury in Mice through Activation of the ERK Pathway

Figure 5

OA-induced ERK phosphorylation in the lung tissue and in A549 lung epithelial cells. Lungs were removed from SW animals 4 h after the OA challenge. Cultured cell lysates were prepared after incubation for 30 min with 100 or 250 μM OA. Graphics in this figure represent densitometric analyses of phosphorylated ERK1/2 and total ERK1/2 bands, as detailed in Methods.