4-1BB/4-1BBL Interaction Promotes Obesity-Induced Adipose Inflammation by Triggering Bidirectional Inflammatory Signaling in Adipocytes/Macrophages

<table>Schematic representation of the bidirectional signal transduction induced by 4-1BB/4-1BBL-mediated interaction between adipocytes and macrophages. The release of inflammatory cytokines (MCP-1, TNF-<i>α</i>, and IL-6) in response to the bidirectional signaling appears to participate in adipose inflammation.</table>

Mediators of Inflammation

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Figure 5

Figure 5: 4-1BB/4-1BBL Interaction Promotes Obesity-Induced Adipose Inflammation by Triggering Bidirectional Inflammatory Signaling in Adipocytes/Macrophages 

Figure 5 | 4-1BB/4-1BBL Interaction Promotes Obesity-Induced Adipose Inflammation by Triggering Bidirectional Inflammatory Signaling in Adipocytes/Macrophages 