Association of Serum Adiponectin, Leptin, and Resistin Concentrations with the Severity of Liver Dysfunction and the Disease Complications in Alcoholic Liver Disease
Table 11
Comparison of the diagnostic accuracy (AUCs) of single variables in the diagnosis of advanced liver dysfunction (MELD ≥ 20) and ALD complications. (univariable analysis)*.
Complication of ALD
Variable
value
AUC (95% CI)
SE
MELD ≥ 20
Acrp30
0.002
0.652 (0.569–0.728)
0.060
CRP
0.004
0.609 (0.527–0.686)
0.058
RBC
0.003
0.675 (0.596–0.747)
0.055
WBC
0.0003
0.656 (0.577–0.730)
0.061
Ascites
0.003
0.652 (0.572–0.725)
0.050
HE
<0.0001
0.666 (0.587–0.739)
0.058
Ascites
Acrp30
0.015
0.621 (0.537–0.700)
0.046
Albumin
<0.0001
0.819 (0.748–0.877)
0.036
ALT
0.0001
0.710 (0.633–0.779)
0.041
AST
0.003
0.606 (0.526–0.683)
0.047
INR
<0.0001
0.808 (0.739–0.866)
0.036
RBC
0.002
0.663 (0.584–0.736)
0.044
WBC
0.008
0.597 (0.517–0.674)
0.045
HE
Acrp30
0.002
0.704 (0.623–0.776)
0.071
AP
0.006
0.652 (0.567–0.730)
0.071
albumin
0.005
0.686 (0.605–0.759)
0.055
T-bilirubin
0.0001
0.770 (0.697–0.833)
0.048
INR
0.0001
0.737 (0.661–0.804)
0.059
PLT
0.035
0.633 (0.553–0.708)
0.057
Ascites
0.012
0.646 (0.567–0.720)
0.056
Renal dysfunction
Resistin
0.001
0.721 (0.641–0.792)
0.060
Albumin
0.034
0.654 (0.572–0.729)
0.059
AST
0.042
0.601 (0.521–0.678)
0.062
AP
0.030
0.677 (0.593–0.753)
0.068
Na
0.012
0.588 (0.508–0.666)
0.080
CRP
0.001
0.714 (0.636–0.784)
0.060
WBC
0.011
0.689 (0.611–0.760)
0.053
RBC
0.031
0.688 (0.610–0.759)
0.059
AUC: area under the ROC curve; SE: standard error; CI: confidence interval.
