Research Article
Characterising Cytokine Gene Expression Signatures in Patients with Severe Sepsis
Table 1
Demographics of patients recruited to study. Values expressed as means and 95% confidence intervals.
| | | Severe sepsis (ICU) | Infection | Control | | | ICU admission | Day 7 ICU |
| | 54 | 32 | 53 | 20 | | Median age (yrs) | 71 (60–76) | 72 (61–79) | 71 (49–81) | 30 (27–33) | | Gender | | | | | | Male | 23 (54%) | 16 (53%) | 33 (62%) | 8 (40%) | | Female | 27 (46%) | 14 (47%) | 20 (38%) | 12 (30%) | | Patient type | | | | | | Surgery | 23 | 20 | — | — | | Medical | 31 | 12 | — | — | | Bacteraemia | | | | | | Gram positive | 10 | — | 24 | — | | Gram negative | 3 | — | 29 | — | | APACHE II | 21 (19–22) | 18.4 (15.7–21.7) | — | — | | SOFA | 12 (9.1–15) | 8.9 (6.9–10.7) | — | — | | SAPS II | 52 (47–57) | 50 (42–58) | — | — | | Septic shock | 42 (84%) | 15 (50%) | — | — | | Respiratory infection | 23 (46%) | 6 (20%) | — | — | | Abdominal infection | 14 (28%) | 16 (53%) | — | — | | Other infection | 13 (26%) | 8 (27%) | — | — |
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SOFA: sequential organ failure assessment score; SAPS II: simplified acute physiology score; APACHE: acute physiology and chronic health evaluation.
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