Review Article

Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View

Table 1

Diagnostic criteria for the systemic inflammatory response syndrome (SIRS).

Defined by the presence of two or more of the following clinical findings

(1) Body temperature >38°C or <36°C
(2) Heart rate >90 min−1
(3) Respiratory rate >20 min−1 or PaCO2 <32 mmHg
(4) White blood cell count >12,000 cells L−1 or <4,000 cells   L−1 or >10% immature (band) forms

Table adapted from [11].