Regulation of Regenerative Periodontal Healing by NAMPT
Figure 4
Effect of various concentrations (0, 30, 100, and 300 ng/mL) of NAMPT on the EMD-induced PDL cell wound fill rate (a). The wound closure, that is, the percentage of fill of the initially cell free zones created by wounding, were analysed over 5 d. All experiments were performed in triplicate and repeated at least twice. Mean ± SEM (); *significantly () different from EMD-treated cells in the absence of NAMPT. Effect of EMD on the expression of BMPR1A, BMPR1B, BMPR2 and TGFβR2 in the presence and absence of NAMPT (100 ng/mL) at 1 d (b). Untreated cells served as control. All experiments were performed in triplicate and repeated at least twice. Mean ± SEM (); *significant () difference between groups.
