Current Perspectives in NSAID-Induced Gastropathy

Table 1

Classification of NSAIDs.

Types	Chemical composition	Common NSAIDs
Salicylates	Derivatives of 2-hydroxybenzoic acid (salicylic acid)	Aspirin, diflunisal, and salsalate
Propionic acid derivatives or “profens”	Derivatives of arylacetic acids	Ibuprofen, dexibuprofen, ketoprofen, dexketoprofen, naproxen, fenoprofen, flurbiprofen, oxaprozin, and loxoprofen
Acetic acid derivatives	Derivatives of acetic acids	Indomethacin, diclofenac, nabumetone, tolmetin, sulindac, etodolac, and ketorolac
Enolic acid derivatives or oxicams	Derivatives of 4-hydroxy benzothiazine heterocycle	Piroxicam, isoxicam, meloxicam, tenoxicam, droxicam, and lornoxicam
Fenamic acid derivatives or fenamates	Derivatives of anthranilic acid	Mefenamic acid, flufenamic acid, tolfenamic acid, and meclofenamic acid
Phenylpyrazolones	Derivatives of 1-aryl-3,5-; pyrazolidinedione	Phenylbutazone, oxyphenbutazone
COX-2 selective inhibitors	Diaryl-5-membered heterocycles	Celecoxib, rofecoxib, and valdecoxib
Anilides and sulphoanilides	Acetamides of aniline with or without a 4-hydroxy or 4-alkoxy group	Acetaminophen, phenacetin, and nimesulide