Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis

Figure 1

Intraperitoneal colony-forming units (CFUs) and survival after CASP. (a)  +  (b) Time course of CFUs on MacConkey (a) and Colombia + CNA (b) agar from peritoneal fluid of WT-CASP mice at 0, 6, 18, 24, and 36 hours after surgery (𝑛=15/group). (c) Comparison of intraperitoneal CFUs between WT CASP and TLR9-D CASP mice 18 h after surgery (𝑛=15/group). (d) Survival rate in WT CASP and TLR9-D CASP following surgery plotted as the Kaplan-Meier survival curve. Curves were significantly different (𝑃=0.0056;  𝑛=10/group; mean  ±  SEM).

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