Review Article

Adipo-Myokines: Two Sides of the Same Coin—Mediators of Inflammation and Mediators of Exercise

Table 3

Concentrations of various factors in conditioned medium from primary human adipocytes and primary human myotubes. Primary human skeletal muscle cells were differentiated for 5 days and primary human preadipocytes were differentiated for 14 days in vitro to mature cells. During the last 24 h cells were incubated with serum-free medium to obtain conditioned medium. Concentrations of secreted factors from cells within this conditioned medium were analyzed by enzyme-linked immunosorbent assay. Data are means ± SEM, .

Secreted factorConcentration in adipocyte-conditioned medium (ng/mL)Concentration in skeletal muscle-conditioned medium (ng/mL)

Chemerin2.12 ± 0.3 [141]0.006 ± 0.001
DPP42.19 ± 1.4 [11]0.69 ± 0.18
IL-60.03 ± 0.002 [141]0.02 ± 0.003
IL-80.15 ± 0.04 0.07 ± 0.01
MCP-10.35 ± 0.060.33 ± 0.08
Myostatin12.64 ± 4.443.44 ± 1.64
PEDF45.7 ± 0.82 [141]5.4 ± 0.86
VEGF0.33 ± 0.09 [141]0.05 ± 0.03