Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1

Figure 1

Effects of PD on survival rates in mice. (a) Chemical structure of PD. (b) Survival rates (𝑛=10). Mice were pretreated intraperitoneally (i.p.) with vehicle (PBS) or PD (15, 45, and 100 mg/kg, resp.) in the presence or absence of ZnPP IX (40 mg/kg) 1 h prior to CLP. Survival rate of mice was monitored for 48 h. ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus the CLP group. ^##𝑃<0.01 versus the CLP-PD group.

(a)

(b)