Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1

Figure 6

Effects of PD on the protein expression (a) and activity (b) of HO in the lungs of mice. Mice were pretreated i.p. with vehicle (PBS) or PD (15, 45, and 100 mg/kg, resp.) in the presence or absence of ZnPP IX (40 mg/kg) 1 h before CLP. The lung tissues were obtained 24 h after CLP for measurement of HO protein expression and activity. Results are expressed as mean ± S.D (𝑛=6). ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus the CLP group. ^##𝑃<0.01 versus the CLP-PD group.

(a)

(b)