PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in  a Mouse Cecal Ligation and Puncture Model

<table>Morphological changes in liver 24 hours after CLP-induced sepsis in hematoxylin and eosin-stained section. Black squares in (a) were magnified into (b), (c), and (d). Spotty necrosis and infiltrations of inflammatory cells were observed in (b). Hepatocytes undergoing ballooning degeneration were observed in (c). Irregular central vein congestion were seen in (d). Original magnification was ×200 for (a) and ×400 for (b), (c), and (d).</table>

Mediators of Inflammation

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Figure 3

Figure 3: PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in  a Mouse Cecal Ligation and Puncture Model 