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Mediators of Inflammation
Volume 2013 (2013), Article ID 381815, 11 pages
http://dx.doi.org/10.1155/2013/381815
Research Article

Alliin, a Garlic (Allium sativum) Compound, Prevents LPS-Induced Inflammation in 3T3-L1 Adipocytes

1Laboratorio de Desarrollo y Regeneración Neural, Instituto de Neurobiología, Departamento de Biología Celular y Molecular, CUCBA, Universidad de Guadalajara, Camino Ing. R. Padilla Sánchez 2100, Las Agujas, 44600 Zapopan, JAL, Mexico
2Departamento de Farmacobiología, CUCEI, Universidad de Guadalajara, Boulevard Marcelino García Barragán, No. 1421, Esquina Calzada Olímpica, 44430 Guadalajara, JAL, Mexico
3Unidad de Farmacología, Departamento de Farmacología y Química Terapéutica, Facultad de Farmacia, Institut de Biomedicina de la UB (IBUB) and CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM)-Instituto de Salud Carlos III, 08028 Barcelona, Spain

Received 10 September 2013; Revised 3 November 2013; Accepted 9 November 2013

Academic Editor: Giuseppe Valacchi

Copyright © 2013 Saray Quintero-Fabián et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary materials include four tables. Table 1-SM. Clusters with an enrichment score of >1.5 and representative genes whose expression is significantly modified by LPS in 3T3-L1 differentiated adipocytes. Table 2-SM. Functional categories and genes included whose expression is significantly modified by alliin treatment in 3T3-L1 differentiated adipocytes. Table 3-SM. Genes highly expressed in 3T3-L1 adipocytes by alliin pretreatment and after LPS stimuli. Table 4-SM. Genes that decrease their expression in 3T3-L1 adipocytes by alliin pretreatment and after LPS stimuli.

  1. Supplementary Tables