Cytokines and chemokines showing an unchanged production amongst groups.
Cytokine
Group 1–6 years
Group 7–17 years
Group ≥18 years
IL-1ra
139.2 (92–185.4)
169.2 (134.7–203.6)
129.6 (101.2–172)
IL-2
10.5 (9.4–12.2)
13.8 (10.2–19.2)
14 (9.4–15.9)
IL-7
12.1 (10.3–14.4)
13.6 (10.9–20)
13.5 (11–17.1)
IL-8
30.9 (23.7–32)
32.6 (28.2–39)
29.3 (24.4–35.9)
IL-9
17.6 (10.9–26.8)
24.6 (20.2–30.5)
23.3 (16.3–31.3)
IL-10
11.4 (9.5–12.8)
11.3 (8.9–13.7)
12.6 (8.5–16.7)
IL-12(p70)
44.3 (39.8–64.1)
34.5 (23.2–48.2)
34.8 (19.6–56.3)
Basic FGF
33.9 (30.8–39.5)
40.1 (35.7–49.3)
41.7 (33.2–49.5)
G-CSF
36.2 (30.3–49.9)
43.8 (39.3–54)
45.5 (34–53.6)
GM-CSF
78.8 (74.6–83)
97.4 (30.1–138.4)
38.3 (26.3–63.8)
IP-10
674.5 (375.4–795.9)
525.8 (387.8–848.9)
576.2 (368.5–808.5)
MCP-1
35.9 (25.6–62)
52 (26.5–77.9)
41.5 (20.1–78.9)
MIP-1α
7.3 (6.6–8.1)
7.4 (6.3–8.2)
7.1 (6.2–9)
RANTES
5753 (4890–6201)
5420 (4889–6091)
5839 (5147–6089)
VEGF
95.6 (81.4–169.3)
73.3 (46–126)
61.6 (32–118.9)
IL-16
151 (110.1–205.7)
155.7 (92.2–213.2)
105.6 (93–166)
CTACK
459 (238.5–549.9)
384.4 (268.2–506.2)
335.9 (190.9–468.6)
HGF
464.5 (270.1–689.2)
389.4 (308.3–506.4)
319.7 (196.6–477.9)
M-CSF
10.8 (8.2–26.9)
12.2 (9.1–17)
9.9 (8.6–13.1)
MIG
354.5 (306.2–393.4)
380.1 (167.4–548.8)
278.2 (138.7–539.9)
Values are expressed as pg/mL, median (IQR); differences amongst groups are not statistically significant () after a Kruskal-Wallis test followed by Dunn’s multiple comparison test.
