Hyperoxia Exacerbates Postnatal Inflammation-Induced Lung Injury in Neonatal BRP-39 Null Mutant Mice Promoting the M1 Macrophage Phenotype

Figure 3

BRP-39 decreases with hyperoxia and acts as a marker for the M2 phenotype in macrophages. BRP-39 mRNA levels in mouse RAW macrophages after 16 h of stimulation with lipopolysaccharide (LPS; 100 ng/mL) (a) or interleukin-4 (IL-4; 10 ng/mL) (b). Results expressed as the mean ± SEM of data obtained from three independent experiments. C: control (RA); HYP: hyperoxia. ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001.

(a)

(b)