How Histopathology Can Contribute to an Understanding of Defense Mechanisms against Cryptococci

<table>(a) The lung of mice infected with <i>C. neoformans</i> TIMM 0362 showed yeast cell proliferation in the alveoli but showed a very limited response of macrophage (13 days after infection, hematoxylin and eosin (HE) double stain, and original magnification ×200). (b) The lung of mice infected with <i>C. neoformans</i> TIMM 0372 showed numerous multinucleated giant cells (MGCs) due to the prominent macrophage response (13 days after infection, HE double stain, and original magnification ×200).</table>

Mediators of Inflammation

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Figure 1

Figure 1: How Histopathology Can Contribute to an Understanding of Defense Mechanisms against Cryptococci 