Dual Effect of Serum Amyloid A on the Invasiveness of Glioma Cells

Figure 7

Influence of SAA on tumor cells. Glioma cells may be affected by SAA produced by the liver during inflammatory processes (paracrine actions) and by SAA synthesized by the tumor itself (autocrine or intracrine actions). The effect on glioma cell line proliferation, migration, and invasion depends on cell type and concentration of rSAA.