Persistent Inflammation in the CNS during Chronic EAE Despite Local Absence of IL-17 Production
Figure 4
Production of cytokines by CNS infiltrating cells. Female C57BL/6 mice were submitted to EAE induction by immunization with MOG emulsified in CFA and the cytokine production was assayed in acute and chronic stages of EAE. IFN-γ (a), TNF-α (b), IL-17 (c), IL-6 (d), and IL-10 (e) production by cells eluted from the brain stimulated in vitro with MOG. Data were presented by mean ± SE of 6 mice and representative of two independent experiments. * and #.