Dexmedetomidine Inhibits Inflammatory Reaction in Lung Tissues of Septic Rats by Suppressing TLR4/NF-<i>κ</i>B Pathway

<table>Pulmonary inflammation scores of rats from different groups. Sham: sham operation group; CLP: cecal ligation and puncture operation group; Small: 5 <i>μ</i>g/kg dexmedetomidine treatment group; Medium: 10 <i>μ</i>g/kg dexmedetomidine treatment group; Large: 20 <i>μ</i>g/kg dexmedetomidine treatment group. Data are expressed as <svg height="11.8" id="M6" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 75.787498 11.8" width="75.787498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, <svg height="11.125" id="M7" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.017,-0,0,-.017,7.675,13.688)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
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</svg>, versus sham group; <svg height="15.775" id="M9" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 67.387497 15.775" width="67.387497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, versus CLP group. </table>

Mediators of Inflammation

fig3

Figure 3

Figure 3: Dexmedetomidine Inhibits Inflammatory Reaction in Lung Tissues of Septic Rats by Suppressing TLR4/NF-<i>κ</i>B Pathway 

Mediators of Inflammation

Dexmedetomidine Inhibits Inflammatory Reaction in Lung Tissues of Septic Rats by Suppressing TLR4/NF-κB Pathway

Figure 3