Dexmedetomidine Inhibits Inflammatory Reaction in Lung Tissues of Septic Rats by Suppressing TLR4/NF-κB Pathway
Figure 8
Effect of dexmedetomidine on NF-κB p-65 activation in lung tissues of septic rats by immunohistochemistry staining. Sham: sham operation group; CLP: cecal ligation and puncture operation group; Small: 5 μg/kg dexmedetomidine treatment group; Medium: 10 μg/kg dexmedetomidine treatment group; Large: 20 μg/kg dexmedetomidine treatment group. The degree of NF-κB activation was indicated as percentage of nuclear NF-κB p-65 positive cells to total alveolar epithelial cells. Data are expressed as , . , versus sham group; , versus CLP group.
