Lung-Derived Mediators Induce Cytokine Production in Downstream Organs via an NF-κB-Dependent Mechanism

Figure 5

Physiological parameters during in vivo ventilation. Peak inspiratory pressure (PIP) (solid line, left axis) was determined every 15 minutes; arterial partial pressure of oxygen over fraction of inspired oxygen (PaO₂/FiO₂) (dashed line, right axis) was determined at time 0, 120, and 240 minutes of in vivo mechanical ventilation. *𝑃< 0.05 versus time 0, ±SEM.