Implication of Low HDL-c Levels in Patients with Average LDL-c Levels: A Focus on Oxidized LDL, Large HDL Subpopulation, and Adiponectin
Table 1
Anthropometric data and general characterization of the study groups.
Parameters
Control group
Patients group
Normal HDL ()
Low HDL ()
Normal HDL ()
Low HDL ()
Age (years)
57.6 ± 8.3 55.2–59.9
57.9 ± 9.3 53.8–62.0
0.893
62.0 ± 9.9 (13.0)
60.0 ± 9.1 (14.0)
0.629
BMI (Kg/m2)
27.0 ± 3.6 26.0–28.0
28.8 ± 5.7 26.2–31.3
0.195
29.2 ± 4.8 28.3–30.1
29.9 ± 4.4 28.6–31.1
0.391
WC (cm)
96.5 ± 11.7 93.1–99.8
98.7 ± 12.9 93.0–104.5
0.468
103.5 ± 12.9 101.0–105.9
102.4 ± 13.5 98.2–106.5
0.644
SBP (mmHg)
140 ± 20 135–146
155 ± 21 145–164
0.007
140 ± 23 136–144
135 ± 22 129–141
0.164
DBP (mmHg)
84.9 ± 10.2 82.0–87.9
93.0 ± 10.3 88.5–97.6
0.003
78.0 ± 12.9 75.7–80.4
75.4 ± 13.6 71.5–79.2
0.234
Glucose (mmol/L)
5.42 ± 0.61 5.24–5.59
5.31 ± 0.45 5.11–5.52
0.494
6.38 ± 3.74 (4.86)
8.49 ± 4.12 (6.66)
0.228
HbA1c (%)
6.04 ± 0.49 5.59–6.50
6.30 ± 0.30 5.55–7.05
0.641
8.12 ± 1.92 7.68–8.57
9.38 ± 2.20 8.58–10.17
0.004
Results are presented as mean ± SD, lower and upper bound 95% confidence interval for mean, and values obtained using independent samples -test in the normal distribution samples and as median ± SD, interquartile range, and values obtained using Mann-Whitney test in the non-normal distribution samples. BMI: body mass index; HbA1c: glycated hemoglobin; SBP: systolic blood pressure; DBP: diastolic blood pressure; WC: waist circumference.
