- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Mediators of Inflammation
Volume 2013 (2013), Article ID 615745, 9 pages
Elevated Osteopontin Levels in Mild Cognitive Impairment and Alzheimer’s Disease
1Department of Neurology, Bei Jing Daopei Hospital, Bei Jing 100749, China
2Department of Emergency, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, China
3Department of Paediatrics, Daqing Oilfied General Hospital, Daqing 163311, China
4Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
Received 15 November 2012; Revised 30 January 2013; Accepted 14 February 2013
Academic Editor: Muzamil Ahmad
Copyright © 2013 Yuan Sun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- K. Blennow, M. J. de Leon, and H. Zetterberg, “Alzheimer's disease,” The Lancet, vol. 368, no. 9533, pp. 387–403, 2006.
- O. Hansson, H. Zetterberg, P. Buchhave, E. Londos, K. Blennow, and L. Minthon, “Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study,” Lancet Neurology, vol. 5, no. 3, pp. 228–234, 2006.
- J. C. Morris, M. Storandt, D. W. McKeel et al., “Cerebral amyloid deposition and diffuse plaques in “normal” aging: evidence for presymptomatic and very mild Alzheimer's disease,” Neurology, vol. 46, no. 3, pp. 707–719, 1996.
- A. Okello, P. Edison, H. A. Archer et al., “Microglial activation and amyloid deposition in mild cognitive impairment: a PET study,” Neurology, vol. 72, no. 1, pp. 56–62, 2009.
- A. Ciaramella, F. Bizzoni, F. Salani et al., “Increased pro-inflammatory response by dendritic cells from patients with Alzheimer's disease,” Journal of Alzheimer's Disease, vol. 19, no. 2, pp. 559–572, 2010.
- W. S. T. Griffin, L. C. Stanley, C. Ling et al., “Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease,” Proceedings of the National Academy of Sciences of the United States of America, vol. 86, no. 19, pp. 7611–7615, 1989.
- L. Bergamaschini, S. Canziani, B. Bottasso, M. Cugno, P. Braidotti, and A. Agostoni, “Alzheimer's β-amyloid peptides can activate the early components of complement classical pathway in a C1q-independent manner,” Clinical and Experimental Immunology, vol. 115, no. 3, pp. 526–533, 1999.
- A. Nath, E. Hall, M. Tuzova, et al., “Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheime’s disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development,” NeuroMolecular Medicine, vol. 3, no. 1, pp. 29–39, 2003.
- D. L. Brody and D. M. Holtzman, “Active and passive immunotherapy for neurodegenerative disorders,” Annual Review of Neuroscience, vol. 31, pp. 175–193, 2008.
- L. W. Fisher, D. A. Torchia, B. Fohr, M. F. Young, and N. S. Fedarko, “Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontin,” Biochemical and Biophysical Research Communications, vol. 280, no. 2, pp. 460–465, 2001.
- M. A. Chellaiah and K. A. Hruska, “The integrin αvβ3 and CD44 regulate the actions of osteopontin on osteoclast motility,” Calcified Tissue International, vol. 72, no. 3, pp. 197–205, 2003.
- K. X. Wang and D. T. Denhardt, “Osteopontin: role in immune regulation and stress responses,” Cytokine and Growth Factor Reviews, vol. 19, no. 5-6, pp. 333–345, 2008.
- H. J. Cho and H. S. Kim, “Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification,” Current Atherosclerosis Reports, vol. 11, no. 3, pp. 206–213, 2009.
- M. Jansson, V. Panoutsakopoulou, J. Baker, L. Klein, and H. Cantor, “Cutting edge: attenuated experimental autoimmune encephalomyelitis in ETA-1/osteopontin-deficient mice,” Journal of Immunology, vol. 168, no. 5, pp. 2096–2099, 2002.
- D. Chabas, S. E. Baranzini, D. Mitchell et al., “The influence of the proinflammatory cytokine, osteopontin, on autoimmue demyelinating desease,” Science, vol. 294, no. 5547, pp. 1731–1735, 2001.
- P. K. Petrow, K. M. Hummel, J. Schedel et al., “Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts,” Arthritis and Rheumatism, vol. 43, no. 7, pp. 1597–1605, 2000.
- R. Mishima, F. Takeshima, T. Sawai et al., “High plasma osteopontin levels in patients with inflammatory bowel disease,” Journal of Clinical Gastroenterology, vol. 41, no. 2, pp. 167–172, 2007.
- C. K. Wong, L. C. W. Lit, L. S. Tam, E. K. Li, and C. W. K. Lam, “Elevation of plasma osteopontin concentration is correlated with disease activity in patients with systemic lupus erythematosus,” Rheumatology, vol. 44, no. 5, pp. 602–606, 2005.
- G. F. Weber and H. Cantor, “Differential roles of osteopontin/Eta-1 in early and late lpr disease,” Clinical and Experimental Immunology, vol. 126, no. 3, pp. 578–583, 2001.
- Y. Yokosaki, K. Tanaka, F. Higashikawa, K. Yamashita, and A. Eboshida, “Distinct structural requirements for binding of the integrins αvβ6, αvβ3, αvβ5, α5β1 and α9β1 to osteopontin,” Matrix Biology, vol. 24, no. 6, pp. 418–427, 2005.
- G. F. Weber, S. Ashkar, M. J. Glimcher, and H. Cantor, “Receptor-ligand interaction between CD44 and osteopontin (Eta-1),” Science, vol. 271, no. 5248, pp. 509–512, 1996.
- H. Cantor and M. L. Shinohara, “Regulation of T-helper-cell lineage development by osteopontin: the inside story,” Nature Reviews Immunology, vol. 9, no. 2, pp. 137–141, 2009.
- L. J. Chi, H. T. Lu, G. L. Li et al., “Involvement of T helper type 17 and regulatory T cell activity in tumour immunology of bladder carcinoma,” Clinical and Experimental Immunology, vol. 161, no. 3, pp. 480–489, 2010.
- L. J. Chi, W. H. Xu, Z. W. Zhang, H. T. Huang, L. M. Zhang, and J. Zhou, “Distribution of Th17 cells and Th1 cells in peripheral blood and cerebrospinal fluid in chronic inflammatory demyelinating polyradiculoneuropathy,” Journal of the Peripheral Nervous System, vol. 15, no. 4, pp. 345–356, 2010.
- E. M. Hur, S. Youssef, M. E. Haws, S. Y. Zhang, R. A. Sobel, and L. Steinman, “Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells,” Nature Immunology, vol. 8, no. 1, pp. 74–83, 2007.
- M. Carecchio and C. Comi, “The role of osteopontin in neurodegenerative diseases,” Journal of Alzheimer's Disease, vol. 25, no. 2, pp. 179–185, 2011.
- J. K. Wung, G. Perry, A. Kowalski et al., “Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain,” Current Alzheimer Research, vol. 4, no. 1, pp. 67–72, 2007.
- A. H. Simonsen, J. McGuire, O. Hansson et al., “Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment,” Archives of Neurology, vol. 64, no. 3, pp. 366–370, 2007.
- C. Comi, M. Carecchio, A. Chiocchetti et al., “Osteopontin is increased in the cerebrospinal fluid of patients with Alzheimer's disease and its levels correlate with cognitive decline,” Journal of Alzheimer's Disease, vol. 19, no. 4, pp. 1143–1148, 2010.
- O. Wirths, H. Breyhan, A. Marcello, M. C. Cotel, W. Brück, and T. A. Bayer, “Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease,” Neurobiology of Aging, vol. 31, no. 5, pp. 747–757, 2010.
- M. F. Folstein, S. E. Folstein, and P. R. McHugh, “‘Mini mental state’. A practical method for grading the cognitive state of patients for the clinician,” Journal of Psychiatric Research, vol. 12, no. 3, pp. 189–198, 1975.
- G. McKhann, D. Drachman, and M. Folstein, “Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease,” Neurology, vol. 34, no. 7, pp. 939–944, 1984.
- Diagnostic and Statistical Manual of Mental Disorders DSM-IV-R, American Psychiatric Association, 1994.
- C. P. Hughes, L. Berg, and W. L. Danziger, “A new clinical scale for the staging of dementia,” British Journal of Psychiatry, vol. 140, no. 6, pp. 566–572, 1982.
- R. C. Petersen, “Mild cognitive impairment as a diagnostic entity,” Journal of Internal Medicine, vol. 256, no. 3, pp. 183–194, 2004.
- B. Winblad, K. Palmer, M. Kivipelto, V. Jelic, and L. Fratiglioni, “Mild cognitive impairment: beyond controversies, towards a consensus,” Journal of Internal Medicine, vol. 256, no. 3, pp. 181–182, 2004.
- M. Binder, S. Christoph, B. Sehnert et al., “Elevated serum osteopontin levels in idiopathic retroperitoneal fibrosis,” Clinical and Experimental Rheumatology, vol. 30, no. 5, pp. 772–775, 2012.
- M. Comabella, I. Pericot, R. Goertsches et al., “Plasma osteopontin levels in multiple sclerosis,” Journal of Neuroimmunology, vol. 158, no. 1-2, pp. 231–239, 2005.
- W. Maetzler, D. Berg, N. Schalamberidze et al., “Osteopontin is elevated in Parkinson's disease and its absence leads to reduced neurodegeneration in the MPTP model,” Neurobiology of Disease, vol. 25, no. 3, pp. 473–482, 2007.
- M. L. Shinohara, J. H. Kim, V. A. Garcia, and H. Cantor, “Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin,” Immunity, vol. 29, no. 1, pp. 68–78, 2008.
- M. Saresella, E. Calabrese, I. Marventano et al., “Increased activity of Th-17 and Th-9 lymphocytes and a skewing of the post-thymic differentiation pathway are seen in Alzheimer's disease,” Brain, Behavior, and Immunity, vol. 25, no. 3, pp. 539–547, 2011.
- Neuroinflammation Working Group, “Inflammation and Alzheimer’s disease,” Neurobiology of Aging, vol. 21, no. 3, pp. 383–421, 2000.
- J. M. Ringman, H. Schulman, C. Becker et al., “Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations,” Archives of Neurology, vol. 69, no. 1, pp. 96–104, 2012.
- W. Maetzler, J. Michelis, J. Tomiuk et al., “A single-nucleotide polymorphism of the osteopontin gene may contribute to a susceptibility to Lewy body disease,” Journal of Neural Transmission, vol. 116, no. 5, pp. 599–605, 2009.
- T. Town, J. Tan, R. A. Flavell, and M. Mullan, “T-cells in Alzheimer's disease,” NeuroMolecular Medicine, vol. 7, no. 3, pp. 255–264, 2005.