Table 1: Clinical details and laboratory findings of HC, OND, MCI, and AD patients.

HCONDMCIncMCIcADnADc

Individuals, no.202018131718
Gender, no. of female/male10/1011/98/109/411/68/10
Mean age (mean ± SD)72 (57–81)71 (58–82)73 (59–83)72 (60–82)73 (61–81)74 (59–83)
MMSE score
(mean ± SD)
29 ± 1.528 ± 1.727.1 ± 1.427.9 ± 1.622.9 ± 2.718.9 ± 4.3
OPN plasma levels (ng/mL)
(mean ± SD)
51.4 ± 9.853.3 ± 10.3 52.3 ± 11.753.7 ± 11.174.4±13.754.8 ± 10.1
OPN CSF levels
(mean ± SD)
134.5 ± 19.3128.6 ± 17.7 173.2 ± 20.6226.5 ± 21.2 165.6 ± 20.4
A CSF levels (pg/mL)
(mean ± SD)
326.7 ± 45.8361.2 ± 48.1181.7 ± 32.6167.8 ± 26.9196.3 ± 29.6
Tau CSF levels (pg/mL)
(mean ± SD)
112 ± 21.6141 ± 25.8243.7 ± 31.6275.4 ± 34.9289.6 ± 38.9

HC: healthy control; OND: non-inflammatory neurologic diseases; MCInc: MCI non-converters; MCIc: MCI converters; Adn: newly diagnosed AD; ADc: chronical AD; OPN: osteopontin; SD: standard deviation.