Etanercept Attenuates Traumatic Brain Injury in Rats by Reducing Brain TNF-α Contents and by Stimulating Newly Formed Neurogenesis
Figure 3
Mean ± standard deviation values of the number of BrdU-DCX-positive cells in the core ischemic cortex. Sham-TBI (white column): rats given a sham traumatic brain injury (TBI) operation; TBI + V (lined column): TBI rats treated with vehicle solution; TBI + E (crossed column): TBI rats treated with etanercept solution. The data were obtained 7 days after TBI or sham-TBI operation (). * compared with the sham-TBI group; + compared with the TBI + V group. Right panels depict representative DCX-BrdU double stainings for one sham-TBI rat, one TBI + V rat, and one TBI + E rat.
