- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Mediators of Inflammation
Volume 2013 (2013), Article ID 620837, 9 pages
Etanercept Attenuates Traumatic Brain Injury in Rats by Reducing Brain TNF-α Contents and by Stimulating Newly Formed Neurogenesis
1Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan
2Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan
3Department of Surgery and Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan
4Department of Surgery, Chi Mei Medical Center, Yung-Kang, Tainan, Taiwan
5The Ph.D. Program for Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan
Received 29 January 2013; Revised 25 March 2013; Accepted 25 March 2013
Academic Editor: Freek Zijlstra
Copyright © 2013 Chong-Un Cheong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- S. Chirumamilla, D. Sun, M. R. Bullock, and R. J. Colello, “Traumatic brain injury induced cell proliferation in the adult mammalian central nervous system,” Journal of Neurotrauma, vol. 19, no. 6, pp. 693–703, 2002.
- A. C. Rice, A. Khaldi, H. B. Harvey et al., “Proliferation and neuronal differentiation of mitotically active cells following traumatic brain injury,” Experimental Neurology, vol. 183, no. 2, pp. 406–417, 2003.
- T. Itoh, T. Satou, S. Nishida, S. Hashimoto, and H. Ito, “Immature and mature neurons coexist among glial scars after rat traumatic brain injury,” Neurological Research, vol. 29, no. 7, pp. 734–742, 2007.
- J. R. Kuo, C. J. Lo, C. P. Chang, H. J. Lin, M. T. Lin, and C. C. Chio, “Brain cooling-stimulated angiogenesis and neurogenesis attenuated traumatic brain injury in rats,” Journal of Trauma, vol. 69, no. 6, pp. 1467–1472, 2010.
- F. H. Gage, “Mammalian neural stem cells,” Science, vol. 287, no. 5457, pp. 1433–1438, 2000.
- R. McKay, “Stem cells in the central nervous system,” Science, vol. 276, no. 5309, pp. 66–71, 1997.
- S. Couillard-Despres, B. Winner, S. Schaubeck et al., “Doublecortin expression levels in adult brain reflect neurogenesis,” European Journal of Neuroscience, vol. 21, no. 1, pp. 1–14, 2005.
- J. P. Brown, S. Couillard-Després, C. M. Cooper-Kuhn, J. Winkler, L. Aigner, and H. G. Kuhn, “Transient expression of doublecortin during adult neurogenesis,” Journal of Comparative Neurology, vol. 467, no. 1, pp. 1–10, 2003.
- J. Nacher, C. Crespo, and B. S. McEwen, “Doublecortin expression in the adult rat telencephalon,” European Journal of Neuroscience, vol. 14, no. 4, pp. 629–644, 2002.
- P. K. Dash, S. A. Mach, and A. N. Moore, “Enhanced neurogenesis in the rodent hippocampus following traumatic brain injury,” Journal of Neuroscience Research, vol. 63, pp. 313–319, 2001.
- S. J. Campbell, Y. Jiang, A. E. M. Davis et al., “Immunomodulatory effects of etanercept in a model of brain injury act through attenuation of the acute-phase response,” Journal of Neurochemistry, vol. 103, no. 6, pp. 2245–2255, 2007.
- C. C. Chio, J. W. Lin, M. W. Chang et al., “Therapeutic evaluation of etanercept in a model of traumatic brain injury,” Journal of Neurochemistry, vol. 115, no. 4, pp. 921–929, 2010.
- T. K. McIntosh, L. Noble, B. Andrews, and A. I. Faden, “Traumatic brain injury in the rat: characterization of a midline fluid-percussion model,” Central Nervous System Trauma, vol. 4, no. 2, pp. 119–134, 1987.
- E. Shohami, M. Novikov, and R. Bass, “Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat,” Brain Research, vol. 674, no. 1, pp. 55–62, 1995.
- M. W. Chang, M. S. Young, and M. T. Lin, “An inclined plane system with microcontroller to determine limb motor function of laboratory animals,” Journal of Neuroscience Methods, vol. 168, no. 1, pp. 186–194, 2008.
- Y. Wang, S. Z. Lin, A. L. Chiou, L. R. Williams, and B. J. Hoffer, “Glial cell line-derived neurotrophic factor protects against ischemia- induced injury in the cerebral cortex,” Journal of Neuroscience, vol. 17, no. 11, pp. 4341–4348, 1997.
- R. L. Zhang, Z. G. Zhang, L. Zhang, and M. Chopp, “Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia,” Neuroscience, vol. 105, no. 1, pp. 33–41, 2001.
- D. Sun, R. J. Colello, W. P. Daugherty et al., “Cell proliferation and neuronal differentiation in the dentate gyrus in juvenile and adult rats following traumatic brain injury,” Journal of Neurotrauma, vol. 22, no. 1, pp. 95–105, 2005.
- A. Kleindienst, M. J. McGinn, H. B. Harvey, R. J. Colello, R. J. Hamm, and M. R. Bullock, “Enhanced hippocampal neurogenesis by intraventricular S100B infusion is associated with improved cognitive recovery after traumatic brain injury,” Journal of Neurotrauma, vol. 22, no. 6, pp. 645–655, 2005.
- R. Rola, S. Mizumatsu, S. Otsuka et al., “Alterations in hippocampal neurogenesis following traumatic brain injury in mice,” Experimental Neurology, vol. 202, no. 1, pp. 189–199, 2006.
- J. Francis, Y. Chu, A. K. Johnson, R. M. Weiss, and R. B. Felder, “Acute myocardial infarction induces hypothalamic cytokine synthesis,” American Journal of Physiology, vol. 286, no. 6, pp. H2264–H2271, 2004.
- E. L. Tobinick and H. Gross, “Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration,” Journal of Neuroinflammation, vol. 5, article 2, 2008.
- Y. Jiang, R. Deacon, D. C. Anthony, and S. J. Campbell, “Inhibition of peripheral TNF can block the malaise associated with CNS inflammatory diseases,” Neurobiology of Disease, vol. 32, no. 1, pp. 125–132, 2008.
- S. M. Knoblach, L. Fan, and A. I. Faden, “Early neuronal expression of tumor necrosis factor-α after experimental brain injury contributes to neurological impairment,” Journal of Neuroimmunology, vol. 95, no. 1-2, pp. 115–125, 1999.
- T. Genovese, E. Mazzon, C. Crisafulli et al., “Immunomodulatory effects of etanercept in an experimental model of spinal cord injury,” Journal of Pharmacology and Experimental Therapeutics, vol. 316, no. 3, pp. 1006–1016, 2006.
- C. Lois and A. Alvarez-Buylla, “Long-distance neuronal migration in the adult mammalian brain,” Science, vol. 264, no. 5162, pp. 1145–1148, 1994.
- H. G. Kuhn, H. Dickinson-Anson, and F. H. Gage, “Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation,” Journal of Neuroscience, vol. 16, no. 6, pp. 2027–2033, 1996.
- J. M. Parent, T. W. Yu, R. T. Leibowitz, D. H. Geschwind, R. S. Sloviter, and D. H. Lowenstein, “Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus,” Journal of Neuroscience, vol. 17, no. 10, pp. 3727–3738, 1997.
- A. Chiaretti, A. Antonelli, O. Genovese et al., “Nerve growth factor and doublecortin expression correlates with improved outcome in children with severe traumatic brain injury,” Journal of Trauma, vol. 65, no. 1, pp. 80–85, 2008.
- U. Scherbel, R. Raghupathi, M. Nakamura et al., “Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury,” Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 15, pp. 8721–8726, 1999.
- E. Shohami, I. Ginis, and J. M. Hallenbeck, “Dual role of tumor necrosis factor alpha in brain injury,” Cytokine and Growth Factor Reviews, vol. 10, no. 2, pp. 119–130, 1999.
- H. Neumann, R. Schweigreiter, T. Yamashita, K. Rosenkranz, H. Wekerle, and Y. A. Barde, “Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism,” Journal of Neuroscience, vol. 22, no. 3, pp. 854–862, 2002.
- A. J. Williams, H. H. Wei, J. R. Dave, and F. C. Tortella, “Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat,” Journal of Neuroinflammation, vol. 4, article 17, 2007.
- D. Bermpohl, Z. You, E. H. Lo, H. H. Kim, and M. J. Whalen, “TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice,” Journal of Cerebral Blood Flow and Metabolism, vol. 27, no. 11, pp. 1806–1818, 2007.
- T. Oshima, S. Lee, A. Sato, S. Oda, H. Hirasawa, and T. Yamashita, “TNF-α contributes to axonal sprouting and functional recovery following traumatic brain injury,” Brain Research, vol. 1290, pp. 102–110, 2009.
- N. P. Whitney, T. M. Eidem, H. Peng, Y. Huang, and J. C. Zheng, “Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders,” Journal of Neurochemistry, vol. 108, no. 6, pp. 1343–1359, 2009.
- C. T. Ekdahl, J. H. Claasen, S. Bonde, Z. Kokaia, and O. Lindvall, “Inflammation is detrimental for neurogenesis in adult brain,” Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 23, pp. 13632–13637, 2003.
- Y. P. Liu, H. I. Lin, and S. F. Tzeng, “Tumor necrosis factor-α and interleukin-18 modulate neuronal cell fate in embryonic neural progenitor culture,” Brain Research, vol. 1054, no. 2, pp. 152–158, 2005.
- R. B. Rock, G. Gekker, S. Hu et al., “Role of microglia in central nervous system infections,” Clinical Microbiology Reviews, vol. 17, no. 4, pp. 942–964, 2004.