Increased Serum Levels and Chondrocyte Expression of Nesfatin-1 in Patients with Osteoarthritis and Its Relation with BMI, hsCRP, and IL-18

Table 1

Characteristics of patients with knee OA and healthy, non-OA controls.

Characteristic	OA (𝑛=40)	Controls (𝑛=25)	p1	p2
Age (years)	66.17 ± 5.82	61.52 ± 6.45	>0.05
Gender (F/M)	26/14	16/9
BMI (kg/m^2)	25.34 ± 2.81	25.06 ± 1.71	>0.05
S-nesfatin-1 (pg/mL)	466.45 ± 175.83	352.05 ± 137.51	<0.05
SF-nesfatin-1 (pg/mL)	98.96 ± 47.97	NM		<0.001
hsCRP (mg/L)	3.82 ± 2.88
PIIANP (ng/mL)	12.17 ± 1.77
IL-18 (pg/mL)	218.99 ± 98.42

OA: osteoarthritis; F: female; M: male; BMI: body mass index; S: serum; SF: synovial fluid; NM: not measured.
p1: OA versus controls.
p2: OA SF-nesfatin-1 versus OA S-nesfatin-1.