Modulation of Conjunctival Goblet Cell Function by Inflammatory Cytokines
Figure 5
Inflammatory cytokines alter carbachol-mediated MUC5AC secretion by goblet cells. Cultured goblet cells were treated for 24 h with IFN-γ, TNF-α, IL-6, or IL-17A (10 ng/mL), stimulated with the cholinergic agonist carbachol (10-3 M) for 1 h, and MUC5AC secretion in the supernatants was evaluated by ELISA. *.
