Expression of Inflammation-Related Genes Is Altered in Gastric Tissue of Patients with Advanced Stages of NAFLD
Table 2
List of genes significantly upregulated in gastric tissues of patients with the following pathological conditions.
Genes
Fold change
values
FDR significance (B-H pass test)
Advanced liver inflammation (score ≥ 3)/mild or no liver inflammation (score < 3)
CCL4
2.32
0.037635
Yes
CXCL2
2.82
0.031209
Yes
CCR5
3.16
0.025748
Yes
IFNA2
3.91
0.028306
Yes
IL19
3.48
0.025748
Yes
IL1F8
4.03
0.029948
Yes
CXCL6
4.3
0.037635
Yes
IL8
4.82
0.025748
Yes
Advanced steatosis (score ≥ 3)/mild or no steatosis (score < 3)
IL8RB
1.56
0.027891
Yes
CXCL14
1.77
0.033865
Yes
IL1F10
2.24
0.049141
Yes
NASH/No NASH‡
CCR9
2.96
0.047583
Yes
CCR3
3.44
0.047583
Yes
IL1RN
3.95
0.021559
Yes
IL9
9.49
0.021363
Yes
IL8RA
15.04
0.040682
Yes
Fibrosis presence/no fibrosis‡
CCL17
4.81
0.029
Yes
Advanced liver inflammation (score ≥ 3) (), advanced steatosis (score ≥ 3) (), NASH‡ (), fibrosis (). ‡Comparison was performed for groups of patients without the condition listed. NASH: nonalcoholic steatohepatitis.
