Ox-LDL Promotes Migration and Adhesion of Bone Marrow-Derived Mesenchymal Stem Cells via Regulation of MCP-1 Expression
Figure 2
Ox-LDL promotes transmigration of bmMSCs and enhances cell adhesion between bmMSCs (grey color) and monocytes (red color). (a) Transmigration rates of bmMSCs after exposure to 0, 5, 10, and 20 μg/mL ox-LDL for 6 hours; (b) transmigration rates of bmMSCs after exposure to 10 μg/mL for 0, 3, 6, and 12 hours; (c) the merged phase contrast and fluorescence images show adhesion between bmMSCs and monocytes after treatment with 0, 5, 10, and 20 μg/mL ox-LDL for 6 hours; (d) the merged phase contrast and fluorescence images show adhesion between bmMSCs and monocytes after treatment with 10 μg/mL for 0, 3, 6, and 12 hours; (e) the relative adhesive rate of monocytes onto bmMSCs after treatment with 0, 5, 10 and 20 μg/mL ox-LDL for 6 hours; (f) the relative adhesive rate of monocytes onto bmMSCs after treatment with 10 μg/mL ox-LDL for 0, 3, 6, and 12 hours. Bar graphs represent mean ± SD ( per group). * versus control.
