Ox-LDL Promotes Migration and Adhesion of Bone Marrow-Derived Mesenchymal Stem Cells via Regulation of MCP-1 Expression
Figure 3
Ox-LDL increases expression of ICAM-1, PECAM-1, and VCAM-1 in a dose-dependent manner in bmMSCs. (a) Immunofluorescence assay shows expression of ICAM-1, PECAM-1 and VACM-1 in bmMSCs exposed to 0, 5, 10 and 20 μg/mL ox-LDL for 6 hour; (b)–(d) Relative fluorescence density of ICAM-1, PECAM-1, and VCAM-1; (e)–(g) Western-blotting assay shows expression of ICAM-1, PECAM-1, and VCAM-1 in bmMSCs exposed to 0, 5, 10, and 20 μg/mL ox-LDL for 6 hours. Bar graphs represent mean ± SD ( per group). * versus Control.
