Research Article

Effects of ω-3 Polyunsaturated Fatty Acids on Plasma Proteome in Rett Syndrome

Figure 1

Silver-stained 2-DE gel of proteins from healthy control (a), untreated RTT (b), and RTT after ω-3 PUFAs supplementation (c). 60 μg of total protein was subjected to nonlinear IPG strips, with a pH range from 3 to 10, followed by SDS-polyacrylamide gradient gel (8–16% T) electrophoresis. Molecular mass and pI markers are indicated along the gels. Numbers denote the mass spectrometry-identified protein spots which are listed in Tables 1 and 2. The same protein spots are reported in 3 representative gels from (a) healthy controls, (b) untreated RTT patients; and (c) ω-3 PUFAs supplemented RTT patients.
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(a)
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(b)
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(c)