Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

<table>MAT reduces clinical signs of EAE. (a) Structure of MAT. (b) Effect-versus-time curves of MAT effects on EAE. Clinical EAE was scored daily after immunization according to a 0–5 scale. (c) The mean maximum clinical scores are expressed as mean ± SD (<svg height="11.225" id="M1" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 44.400002 11.225" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, compared to vehicle-treated group.</table>

Mediators of Inflammation

fig1

Figure 1

Figure 1: Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis 