Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

Figure 2

CNS infiltration and demyelination. At day 17 p.i., spinal cord lumbar enlargements were harvested and transverse sections were stained with H&E and C-2R-B. (a) Digital images were collected under bright-field setting using a ×40 objective. (b) Quantitative analysis. Mean values and SD are shown (𝑛=8 each group). ^△△𝑃<0.01, compared to naive group; ^∗∗𝑃<0.01, compared to vehicle-treated group; ^#𝑃<0.05 and ^##𝑃<0.01, compared to DEX group; ^◊𝑃<0.05 and ^◊◊𝑃<0.01, comparison between MAT-L and MAT-H groups.

(a)

(b)