Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

Figure 3

BBB integrity. Evans Blue was i.v. injected at day 17 p.i. and brains were harvested at 60 min to determine Evans Blue extravasation. Results are expressed as mean ± SD (𝑛=8 each group). ^△△𝑃<0.01, compared to naive group; ^∗∗𝑃<0.01, compared to vehicle group; ^##𝑃<0.01, compared to DEX group; ^◊𝑃<0.05, comparison between MAT-L and MAT-H groups.