Association of CFH and CFB Gene Polymorphisms with Retinopathy in Type 2 Diabetic Patients
Table 1
Demographic and clinical characteristics of the study subjects.
Characteristic
DR ( = 277)
DM ( = 275)
value
Age (years)
55.5 ± 14.0
56.3 ± 7.6
0.44
Gender (F/M)
144/133
153/122
0.39
Duration of diabetes (years)
13.6 ± 7.1
18.1 ± 6.7
<0.001
Duration of DR (years)
5.0 ± 4.2
none
Gaps between diabetes and DR onset (years)
8.3 ± 6.7
none
HbA1C (%)
8.2 ± 1.7
7.9 ± 1.9
0.09
BMI (kg/m2)
23.7 ± 4.6
24.1 ± 4.4
0.46
Hypertension (%)
71.8
66.9
0.21
Hyperlipidemia (%)
32.1
23.3
<0.01
Smoking (%)
13.4
16.0
0.38
Insulin therapy (%)
45.1
26.2
<0.001
Family history of diabetes (%)
25.6
21.5
0.25
All values were compared by or student -test, < 0.05 as statistically significant. DR: diabetic retinopathy; DM: diabetes mellitus; HbA1c: glycosylated hemoglobin; BMI: body mass index.
