Clinical Study
Association of CFH and CFB Gene Polymorphisms with Retinopathy in Type 2 Diabetic Patients
Table 4
Interaction snalysis between CFH-rs800292 and CFB-rs1048709.
| (a) |
| | Genotype distribution | CFH rs800292 | | CFB rs1048709 | DM ( = 275) | DR ( = 277) | | AA | AG | GG | AA | AG | GG |
| | GG | 35 (12.7) | 53 (19.3) | 52 (18.9) | 21 (7.6) | 57 (20.6) | 42 (15.2) | | AG | 27 (9.8) | 56 (20.4) | 33 (12.0) | 13 (4.7) | 56 (20.2) | 48 (17.3) | | AA | 3 (1.1) | 11 (4.0) | 5 (1.8) | 4 (1.4) | 19 (6.9) | 17 (6.1) |
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| (b) |
| | Joint odds ratios and 95% confidence | CFH rs800292 | | CFB rs1048709 | AA | AG | GG |
| | GG | 1.00 (Ref) | 1.79 (0.93–3.46) | 1.35 (0.68–2.65) | | AG | 0.80 (0.34–1.89) | 1.67 (0.87–3.21) | 2.42 (1.20–4.88) | | AA | 2.22 (0.45–10.92) | 2.88 (1.65–7.22) | 5.67 (1.82–17.62) |
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