Extracellular Signal-Regulated Kinase Is a Direct Target of the Anti-Inflammatory Compound Amentoflavone Derived from Torreya nucifera
Figure 2
Effect of amentoflavone on mRNA expression of proinflammatory genes. (a and b) The mRNA levels of iNOS, COX-2, IL-1β, and TNF-α in RAW264.7 cells pretreated with or without AF (200 μM) for 30 min and then exposed to LPS (1 μg/mL) for 6 h were determined using semiquantitative (a) and real-time (b) PCR. RI: relative intensity. compared to the control.
