The Role of T Cell Immunoglobulin Mucin Domains 1 and 4 in a Herpes Simplex Virus-Induced Behçet’s Disease Mouse Model
Figure 7
The expression of Tim-4+ cells was downregulated after siTim-4 treatment. Tim-4 siRNA was administered intraperitoneally and the frequencies of Tim-4+ cells were analyzed in peritoneal macrophages in normal (Nor) mice by FACS. (a) siTim-4 2, 5, and 10 μg/mouse or negative control siRNA (Con) (2 and 5 μg/mouse) were injected intraperitoneally into Nor mice. (b) Five μg of siTim-4 was injected, and the frequencies of Tim-4+ peritoneal macrophages were analyzed 24, 48, and 72 hours later. Scrambled siRNA was used as the negative control (-4) (**). Con: control siRNA injection into normal mice, siTim-4: Tim-4 siRNA injection to normal mice, Mac: peritoneal macrophage.
