Research Article

Activation of TRPV1 Prevents OxLDL-Induced Lipid Accumulation and TNF-α-Induced Inflammation in Macrophages: Role of Liver X Receptor α

Figure 5

Effect of TRPV1 activation on expression of SR-A, CD36, SR-BI, ABCA1, and ABCG1 in macrophages. BMDMs were incubated with vehicle, (a) evodiamine (125, 250, 500 nM), or (b) capsaicin (2.5, 5, 10 μM) for 24 h. Western blot analysis of protein levels of SR-A, CD36, ABCA1, ABCG1, SR-BI, and α-tubulin. Data are mean ± SD from 5 independent experiments. * versus vehicle-treated cells.
925171.fig.005a
(a)
925171.fig.005b
(b)