Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia
Table 1
Densitometry data expressed in %.
Treatment
Nitrated protein
Total lysate
β-actin
GluN1
Naive
NMDA (2 nmol, i.t.)
NMDA + FeTMPyP (2 nmol, i.t.)
GluN2B
Naive
NMDA (2 nmol, i.t.)
NMDA + FeTMPyP (2 nmol, i.t.)
GLT-1
Naive
NMDA (2 nmol, i.t.)
NMDA + FeTMPyP (2 nmol, i.t.)
GS
Naive
NMDA (2 nmol, i.t.)
NMDA + FeTMPyP (2 nmol, i.t.)
†P < 0.001 compared to vehicle and *P < 0.001 compared to NMDA alone.