Cockroach Allergen Bla g 7 Promotes TIM4 Expression in Dendritic Cells Leading to Th2 Polarization

Figure 2

rBla g 7 induced expression of CD80 and CD86 in dendritic cells (DCs)s. DCs were incubated with rBla g 7 (1000 ng/mL) or LPS (100 ng/mL) for 48 h at 37°C before being analysed by flow cytometry. (a) Numbers within the large gated regions indicate the percentage of matured cells among total cells. (b) The mean ± SEM data represented the percentage of CD80+ or CD86+ DCs for four separate experiments. ^∗𝑃<0.05 in comparison with medium alone control. ^†𝑃<0.05 compared with the response to the corresponding uninhibited control.

(a)

(b)