Research Article

5-Lipoxygenase-Dependent Recruitment of Neutrophils and Macrophages by Eotaxin-Stimulated Murine Eosinophils

Figure 2

Accumulation of different leukocyte subtypes induced by eotaxin: effect of specific antibody neutralization. Eotaxin was preincubated with specific neutralizing monoclonal antibody (hatched bar), or with irrelevant isotype-matched monoclonal antibody (open bar), before i.p. injection in BALB/c mice. Controls (black bar) received eotaxin but no antibody. Peritoneal lavage fluid, collected 4 h later, was used for total leukocyte quantitation. Data are mean ± SEM. **, , for the differences relative to the positive (eotaxin) and specificity (irrelevant antibody) controls. Data from 5–18 experiments.
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